منابع مشابه
Reducing Adverse Events and Hospitalizations Associated with Drug Interactions
A drug-drug interaction is a pharmacokinetic or pharmacodynamic influence of one drug on another, which can reduce the effectiveness of one or both of the interacting drugs or can lead to toxic effects.1 It is estimated that such drug interactions cause up to 2.8% of hospital admissions,2 and they can lead to serious adverse outcomes for patients. One drug combination that has resulted in death...
متن کاملMultifaceted approach to reducing preventable adverse drug events.
Management Case Studies describe approaches to real-life management problems in health systems. Each installment is a brief description of a problem and how it was dealt with. The cases are intended to help readers deal with similar experiences in their own work sites. Problem solving, not hypothesis testing, is emphasized. Successful resolution of the management issue is not a criterion for pu...
متن کاملPharmacogenomics and reducing the frequency of adverse drug events.
Drug toxicity and adverse drug events Pharmacogenomics, as applied to medical practice, offers the promise of reduction in adverse drug events (ADEs), enhanced drug efficacy and selection of patients able to respond to specific agents. This editorial will focus on the history and evolving role of pharmacogenetics and pharmacogenomics as it moves from the basic research laboratory into clinical ...
متن کاملReducing the risk of adverse drug events in older adults.
Adverse drug events occur in 15 percent or more of older patients presenting to offices, hospitals, and extended care facilities. These events are potentially preventable up to 50 percent of the time. Common serious manifestations include falls, orthostatic hypotension, heart failure, and delirium. The most common causes of death are gastrointestinal or intracranial bleeding and renal failure. ...
متن کاملAnticoagulation-associated adverse drug events.
PURPOSE Anticoagulant drugs are among the most common medications that cause adverse drug events (ADEs) in hospitalized patients. We performed a 5-year retrospective study at Brigham and Women's Hospital to determine clinical characteristics, types, root causes, and outcomes of anticoagulant-associated ADEs. METHODS We reviewed all inpatient anticoagulant-associated ADEs, including adverse dr...
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ژورنال
عنوان ژورنال: JAMA
سال: 2016
ISSN: 0098-7484
DOI: 10.1001/jama.2016.16392